Fetal exposure to perfluoroalkyl substances (PFAS) in drinking water and congenital malformations: A nation-wide register-based study on PFAS in drinking water

Modelled fetal sum of PFAS4 was associated with malformations of the nervous system and chromosomal anomalies, while the mixture assessment revealed associations with defects on urinary system. As the underlying toxicological mechanisms remains unclear, further investigation is warranted.

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Publication Details

Journal
Environment International
Published
2025-03-14
DOI
https://doi.org/10.1016/j.envint.2025.109381
Citations
2
Primary Topic
Per- and polyfluoroalkyl substances research
Type
article
Field-Weighted Citation Impact
1.72

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article

Fetal exposure to perfluoroalkyl substances (PFAS) in drinking water and congenital malformations: A nation-wide register-based study on PFAS in drinking water

Melle Säve‐Söderbergh, Carolina Vogs, Tessa Schillemans, Agneta Åkesson et al.
2 citations
Environment International
Per- and polyfluoroalkyl substances research
1.72
article

Fetal exposure to perfluoroalkyl substances (PFAS) in drinking water and congenital malformations: A nation-wide register-based study on PFAS in drinking water

Melle Säve‐Söderbergh, Carolina Vogs, Tessa Schillemans, Agneta Åkesson, Emma Ankarberg, Emilie Helte, Carolina Donat‐Vargas, Lutz Ahrens, Anders Glynn, Irina Gyllenhammar, Emelie Lindfeldt
article en
2 citations

Abstract

Modelled fetal sum of PFAS4 was associated with malformations of the nervous system and chromosomal anomalies, while the mixture assessment revealed associations with defects on urinary system. As the underlying toxicological mechanisms remains unclear, further investigation is warranted.

Environment InternationalVol. 198
National Food Administration (SE), Karolinska Institutet (SE), Swedish University of Agricultural Sciences (SE), Barcelona Institute for Global Health (ES)
Svenska Forskningsrådet Formas, Vetenskapsrådet
Clean water and sanitation
Openalex Percentile: Top 19%
Per- and polyfluoroalkyl substances research
1.72
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Fetal exposure to perfluoroalkyl substances (PFAS) in drinking water and congenital malformations: A nation-wide register-based study on PFAS in drinking water — Melle Säve‐Söderbergh, Carolina Vogs, et al. · Environment International (2025) | TGRS Research Map | TGRS