Associations between blood sex hormones, cognitive decline and incident dementia in community-dwelling older Australian women: a prospective cohort study

The finding of a greater likelihood of a decline in executive function and verbal fluency in community-dwelling older women with the highest blood concentrations of DHEA and its metabolite estrone need reaffirmation and their clinical significance should be further investigated. These findings do not support use of estrogen or DHEA therapy to prevent cognitive decline in older women.

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Publication Details

Journal
Climacteric
Published
2025-03-14
DOI
https://doi.org/10.1080/13697137.2025.2470458
Citations
1
Primary Topic
Menopause: Health Impacts and Treatments
Type
article
Field-Weighted Citation Impact
1.29

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article

Associations between blood sex hormones, cognitive decline and incident dementia in community-dwelling older Australian women: a prospective cohort study

Farhana Sultana, John J. McNeil, Rory Wolfe, Susan R. Davis et al.
1 citations
Climacteric
Menopause: Health Impacts and Treatments
1.29
article

Associations between blood sex hormones, cognitive decline and incident dementia in community-dwelling older Australian women: a prospective cohort study

Farhana Sultana, John J. McNeil, Rory Wolfe, Susan R. Davis, Rakibul M. Islam
article en
1 citations

Abstract

The finding of a greater likelihood of a decline in executive function and verbal fluency in community-dwelling older women with the highest blood concentrations of DHEA and its metabolite estrone need reaffirmation and their clinical significance should be further investigated. These findings do not support use of estrogen or DHEA therapy to prevent cognitive decline in older women.

ClimactericVol. 28(4)
International Centre for Diarrhoeal Disease Research (BD), Alfred Health (AU), Monash University (AU)
Victorian Cancer Agency, Monash University, National Health and Medical Research Council, National Institute on Aging, National Cancer Institute
Gender equality
Openalex Percentile: Top 22%
Menopause: Health Impacts and Treatments
1.29
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Associations between blood sex hormones, cognitive decline and incident dementia in community-dwelling older Australian women: a prospective cohort study — Farhana Sultana, John J. McNeil, et al. · Climacteric (2025) | TGRS Research Map | TGRS