The behavioural effects of the serotonin 1A receptor agonist buspirone on cognition and emotional processing in healthy volunteers
Acute buspirone administration produced a mild impairment in verbal memory and a subtle negative bias in emotional processing in healthy volunteers. These effects are consistent with the mixed effects of buspirone on pre- and post-synaptic 5-HT<sub>1A</sub> receptors.
Authors
- Catherine J. Harmer (ORCID: https://orcid.org/0000-0002-1609-8335)
- Philip J. Cowen (ORCID: https://orcid.org/0000-0001-5518-6138)
- Sorcha Hamilton (ORCID: https://orcid.org/0000-0002-4702-5788)
- Alexander L. W. Smith (ORCID: https://orcid.org/0000-0003-1052-0096)
- Susannah E. Murphy (ORCID: https://orcid.org/0000-0001-8995-2099)
Institutions
- Oxford Health NHS Foundation Trust (GB)
- Warneford Hospital (GB)
- University of Oxford (GB)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1007/s00213-025-06770-6
- Citations
- 1
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.91