Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperature

A delay in centrifugation of samples affected the stability of several analytes evaluated in the study, resulting in changes in their concentration or integrity. The analytical results for these analytes cannot be considered reliable as they do not meet the standards required for clinical validation. This underscores the importance of following stringent pre-analytical protocols to maintain the accuracy and reliability of laboratory diagnostic results.

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Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2025-03-13
DOI
https://doi.org/10.1515/cclm-2025-0109
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
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article

Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperature

Dolors Dot-Bach, Ariadna Arbiol‐Roca, Teresa Escartín-Diez, María Sanz-Felisi et al.
Clinical Chemistry and Laboratory Medicine (CCLM)
Clinical Laboratory Practices and Quality Control
article

Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperature

Dolors Dot-Bach, Ariadna Arbiol‐Roca, Teresa Escartín-Diez, María Sanz-Felisi, Paula Tauler-Quetglas
article en

Abstract

A delay in centrifugation of samples affected the stability of several analytes evaluated in the study, resulting in changes in their concentration or integrity. The analytical results for these analytes cannot be considered reliable as they do not meet the standards required for clinical validation. This underscores the importance of following stringent pre-analytical protocols to maintain the accuracy and reliability of laboratory diagnostic results.

Clinical Chemistry and Laboratory Medicine (CCLM)Vol. 63(8)
Bellvitge University Hospital (ES)
Clean water and sanitation
Openalex Percentile: Top 94%
Clinical Laboratory Practices and Quality Control
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