Circulating PGC-1α and MOTS-c Peptide as Potential Mitochondrial Biomarkers in Patients Undergoing Aortic Valve Replacement
Mitochondria may represent a promising target for studying new pathways involved in AVD. We propose PGC1α and MOTS-c as potential plasma biomarkers for AVD detection. Further studies, including early-stage patients, are necessary to confirm the significance of our findings.
Authors
- Maria J. Sanchez‐Quintero (ORCID: https://orcid.org/0000-0002-5638-2920)
- Miguel Romero‐Cuevas (ORCID: https://orcid.org/0000-0002-8323-0893)
- Laura Martín Chaves
- Mora Murri (ORCID: https://orcid.org/0000-0002-6482-192X)
- Ada del Mar Carmona-Segovia (ORCID: https://orcid.org/0000-0002-2031-2760)
- Bárbara Pozo‐Vilumbrales (ORCID: https://orcid.org/0000-0002-7273-9010)
- Víctor Manuel Becerra‐Muñoz (ORCID: https://orcid.org/0000-0001-6454-7644)
- Francisco Javier Pavón (ORCID: https://orcid.org/0000-0002-5256-8904)
- Jorge Rodríguez‐Capitán (ORCID: https://orcid.org/0000-0001-6650-6264)
- Pilar Martínez López
- Andrea Iboleón
Institutions
- Instituto de Salud Carlos III (ES)
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Clínico Universitario Virgen de la Victoria (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- Universidad de Málaga (ES)
Publication Details
- Journal
- Biologics
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/btt.s504289
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Universidad de Málaga
- European Commission
- Ministerio de Ciencia e Innovación
- Junta de Andalucía
- Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares
- Servicio Andaluz de Salud
- Instituto de Salud Carlos III
- European Regional Development Fund
- European Social Fund