Oral Losartan Treatment Improves Microvascular Endothelial Function via Nitric Oxide-Dependent Mechanisms in Women With a History of Preeclampsia
These data suggest that systemic AT1R-inhibition with oral losartan is a viable, mechanism-specific approach to improve endothelial function and reduce vasoconstrictor sensitivity to angiotensin II in the microvasculature of healthy, normotensive women with a history of preeclampsia.
Authors
- Anna E. Stanhewicz (ORCID: https://orcid.org/0000-0002-3941-3879)
- Kelsey S. Schwartz (ORCID: https://orcid.org/0000-0002-1418-1813)
- Diana I. Jalal (ORCID: https://orcid.org/0000-0002-1975-8650)
Institutions
- University of Iowa (US)
- Iowa City VA Health Care System (US)
- Iowa City VA Medical Center (US)
- University of Iowa Health Care (US)
- Iowa City Public Library (US)
Publication Details
- Journal
- American Journal of Hypertension
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1093/ajh/hpaf033
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.17