Non-high density lipoprotein cholesterol/high density lipoprotein cholesterol is L-shaped associated with all-cause mortality and U-shaped with cardiovascular mortality in hypertensive patients
The findings indicate that lower NHHR is associated with an increased risk of both cardiovascular and all-cause mortality, highlighting the critical need for comprehensive lipid management in the clinical management of hypertension. These results suggest that NHHR could serve as a valuable tool for identifying high-risk individuals for mortality, and should be incorporated into routine risk stratification assessments for hypertensive patients. This could more effectively improve patient prognosis and guide personalized treatment strategies.
Authors
- Meiqian Chen
- Guanzhen Lu
- Qian Liu (ORCID: https://orcid.org/0000-0002-8078-1075)
- Li Zhang (ORCID: https://orcid.org/0000-0002-6672-4808)
- Shuhui Yu (ORCID: https://orcid.org/0000-0003-0219-6564)
- Qingxin Gu
Institutions
- Zhejiang Chinese Medical University (CN)
- Huzhou Normal University (CN)
- Huzhou Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3389/fendo.2025.1490229
- Citations
- 1
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39