Non-high density lipoprotein cholesterol/high density lipoprotein cholesterol is L-shaped associated with all-cause mortality and U-shaped with cardiovascular mortality in hypertensive patients

The findings indicate that lower NHHR is associated with an increased risk of both cardiovascular and all-cause mortality, highlighting the critical need for comprehensive lipid management in the clinical management of hypertension. These results suggest that NHHR could serve as a valuable tool for identifying high-risk individuals for mortality, and should be incorporated into routine risk stratification assessments for hypertensive patients. This could more effectively improve patient prognosis and guide personalized treatment strategies.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-03-13
DOI
https://doi.org/10.3389/fendo.2025.1490229
Citations
1
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
1.39
Controls
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article

Non-high density lipoprotein cholesterol/high density lipoprotein cholesterol is L-shaped associated with all-cause mortality and U-shaped with cardiovascular mortality in hypertensive patients

Meiqian Chen, Guanzhen Lu, Qian Liu, Li Zhang et al.
1 citations
Frontiers in Endocrinology
Blood Pressure and Hypertension Studies
1.39
article

Non-high density lipoprotein cholesterol/high density lipoprotein cholesterol is L-shaped associated with all-cause mortality and U-shaped with cardiovascular mortality in hypertensive patients

Meiqian Chen, Guanzhen Lu, Qian Liu, Li Zhang, Shuhui Yu, Qingxin Gu
article en
1 citations

Abstract

The findings indicate that lower NHHR is associated with an increased risk of both cardiovascular and all-cause mortality, highlighting the critical need for comprehensive lipid management in the clinical management of hypertension. These results suggest that NHHR could serve as a valuable tool for identifying high-risk individuals for mortality, and should be incorporated into routine risk stratification assessments for hypertensive patients. This could more effectively improve patient prognosis and guide personalized treatment strategies.

Frontiers in EndocrinologyVol. 16
Zhejiang Chinese Medical University (CN), Huzhou Normal University (CN), Huzhou Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 22%
Blood Pressure and Hypertension Studies
1.39
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Non-high density lipoprotein cholesterol/high density lipoprotein cholesterol is L-shaped associated with all-cause mortality and U-shaped with cardiovascular mortality in hypertensive patients — Meiqian Chen, Guanzhen Lu, et al. · Frontiers in Endocrinology (2025) | TGRS Research Map | TGRS