Bletilla oligosaccharides improved 5-fluorouracil-induced intestinal mucositis in mice by activating NF-κB signalling pathway and regulating intestinal microbiota
BO can relieve the progress of intestinal mucositis by relieving inflammation, protecting the intestinal epithelial barrier and regulating the intestinal microbiota. These data provide experimental evidence for the application of BO in chemotherapeutic intestinal mucositis.
Authors
- Guoqiang Qian (ORCID: https://orcid.org/0000-0003-3036-1512)
- Yanli Xiong (ORCID: https://orcid.org/0000-0002-1639-103X)
- Shengsuo Ma (ORCID: https://orcid.org/0000-0002-0189-7150)
- Yupeng Jiang (ORCID: https://orcid.org/0000-0001-8971-2079)
- Qiuxiong Yin
- Xinran Li (ORCID: https://orcid.org/0000-0001-8988-7223)
Institutions
- Sun Yat-sen University (CN)
- Guangdong Pharmaceutical University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3389/fphar.2025.1526274
- Citations
- 6
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.11