Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression

Our study provides compelling evidence that TBMS1 suppresses liver cancer progression by inactivating the NF-κB pathway and regulating TNFAIP3 expression. These findings offer novel insights and a theoretical basis for the development of targeted therapies for liver cancer.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2025-03-01
DOI
https://doi.org/10.2147/dddt.s507656
Citations
4
Primary Topic
Natural product bioactivities and synthesis
Type
article
Field-Weighted Citation Impact
3.22
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article

Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression

Liwen Zhu, Langxuan Chen, Zhen Huang, Mingqin Zhou et al.
4 citations
Drug Design Development and Therapy
Natural product bioactivities and synthesis
3.22
article

Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression

Liwen Zhu, Langxuan Chen, Zhen Huang, Mingqin Zhou, Hongzhong Zhou, Haohua Zhang, Yajun Zhang
article en
4 citations

Abstract

Our study provides compelling evidence that TBMS1 suppresses liver cancer progression by inactivating the NF-κB pathway and regulating TNFAIP3 expression. These findings offer novel insights and a theoretical basis for the development of targeted therapies for liver cancer.

Drug Design Development and TherapyVol. Volume 19
Guangzhou University of Chinese Medicine (CN), Southern University of Science and Technology (CN), Shantou University (CN), Cancer Hospital of Shantou University Medical College (CN), Shenzhen Maternity and Child Healthcare Hospital (CN), Shenzhen Second People's Hospital (CN), Shenzhen Third People’s Hospital (CN)
Good health and well-being
Openalex Percentile: Top 9%
Natural product bioactivities and synthesis
3.22
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Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression — Liwen Zhu, Langxuan Chen, et al. · Drug Design Development and Therapy (2025) | TGRS Research Map | TGRS