Major Predominant Serotypes and Virulence Genes and Antibiotic Resistance Characteristics of Klebsiella pneumoniae Clinical Isolates in Middle and East China
K1/K2 were the major predominant hvKp serotypes with <i>rmpA/rmpA2</i> virulence genes and carbapenem-resistant <i>K. pneumoniae</i> strains were prevalent in patients from middle and east China. The hvKp serotypes have low antibiotic resistance, but <i>K. pneumoniae</i> isolates from patients with urinary infections resist the cephalosporin/quinolone antibiotics for treatment of bacterial urinary infections. Amikacin and polymyxin-B can be used to treat drug-resistant <i>K. pneumoniae</i> infections.
Authors
- Jiangfeng Qin (ORCID: https://orcid.org/0000-0002-7186-4821)
- Lihua Tao (ORCID: https://orcid.org/0000-0001-8811-8094)
- Sui-Ning Chen
- Yinhai Xu
- Xinwei Zhang (ORCID: https://orcid.org/0000-0003-4435-361X)
- Jie Yan (ORCID: https://orcid.org/0000-0003-2054-6986)
- Wei Pan (ORCID: https://orcid.org/0000-0001-5345-3829)
- Meiqi Wang (ORCID: https://orcid.org/0000-0002-4290-7044)
- Meijuan Yang (ORCID: https://orcid.org/0000-0001-9096-4687)
- Aihua Sun (ORCID: https://orcid.org/0000-0001-5008-5151)
Institutions
- Xuzhou Medical College (CN)
- Chuzhou University (CN)
- Boxing People's Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
- Hangzhou Medical College (CN)
- Putian University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/idr.s502323
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00