Long-term prognosis of lupus nephritis: comparison between pediatric, adult, and advanced age onset
While children and adults demonstrate comparable long-term kidney survival, elderly patients face significantly worse outcomes due to advanced chronicity and systemic damage. These findings highlight the need for tailored interventions in late-onset LN. Older-onset LN, in fact, was an independent predictor of CKD or death together with AKD, arterial hypertension, SLICC >0, and no remission at 1 year.
Authors
- Marta Calatroni (ORCID: https://orcid.org/0000-0003-4204-758X)
- Laura Locatelli (ORCID: https://orcid.org/0000-0002-4568-7825)
- Antonio Mastrangelo (ORCID: https://orcid.org/0000-0001-5700-7439)
- Simeone Andrulli (ORCID: https://orcid.org/0000-0001-8634-7934)
- Francesco Reggiani (ORCID: https://orcid.org/0000-0001-9254-618X)
- Tommaso Schioppo (ORCID: https://orcid.org/0000-0001-8359-5131)
- Federica Bello (ORCID: https://orcid.org/0000-0003-2878-2254)
- Nicoletta Del Papa (ORCID: https://orcid.org/0000-0003-1549-8852)
- Federico Doti
- Gabriella Moroni (ORCID: https://orcid.org/0000-0003-4955-6061)
- G De Vivo
Institutions
- Humanitas University (IT)
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale San Paolo (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Italian Association for Cancer Research (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
- University of Florence (IT)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1531675
- Citations
- 9
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 15.01
Funders
- Humanitas Research Hospital