Common connective tissue disorder and anti-cytokine autoantibodies are enriched in idiopathic multicentric castleman disease patients
IgG autoantibodies binding autoantigens associated with common CTDs and cytokines are elevated in iMCD patients compared to HC, suggesting that autoimmunity may be involved in iMCD pathogenesis.
Authors
- Xihui Yin (ORCID: https://orcid.org/0000-0002-1861-1147)
- Paul J. Utz (ORCID: https://orcid.org/0000-0003-1181-1565)
- David C. Fajgenbaum (ORCID: https://orcid.org/0000-0002-7367-8184)
- Jochen M. Schwenk (ORCID: https://orcid.org/0000-0001-8141-8449)
- Sarah E. Chang (ORCID: https://orcid.org/0009-0008-9986-1666)
- Saishravan Shyamsundar (ORCID: https://orcid.org/0000-0002-0160-8910)
- Tea Dodig‐Crnković (ORCID: https://orcid.org/0000-0002-2875-896X)
- Michael V. Gonzalez (ORCID: https://orcid.org/0000-0001-9741-475X)
- Melanie Mumau (ORCID: https://orcid.org/0000-0003-2145-8347)
- Kazuyuki Yoshizaki (ORCID: https://orcid.org/0000-0002-1017-7120)
- Mateo Sarmiento Bustamante (ORCID: https://orcid.org/0009-0002-6774-2714)
- Allan Feng (ORCID: https://orcid.org/0000-0003-0122-7947)
- Tarun Garg (ORCID: https://orcid.org/0009-0001-3120-6824)
- Shaurya Dhingra (ORCID: https://orcid.org/0000-0002-5327-7535)
- Frits van Rhee (ORCID: https://orcid.org/0000-0001-9959-1282)
- Müge Kalaycıoğlu (ORCID: https://orcid.org/0009-0006-5224-9926)
Institutions
- Science for Life Laboratory (SE)
- Osaka Research Institute of Industrial Science and Technology (JP)
- University of Pennsylvania (US)
- University of Arkansas for Medical Sciences (US)
- KTH Royal Institute of Technology (SE)
- Stanford University (US)
- The University of Osaka (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1528465
- Citations
- 5
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.36