A duplex one-step recombinase aided PCR assay for the rapid and sensitive detection of the isoniazid resistance genes katG and inhA in Mycobacterium tuberculosis
The DO-RAP can be adopted in ordinary qPCR equipment for the rapid, highly sensitive and specific detection of the isoniazid resistance genes of <i>Mycobacterium tuberculosis</i>.
Authors
- Yanqing Tie
- Xichao Ou (ORCID: https://orcid.org/0000-0002-3126-4450)
- Xinxin Shen (ORCID: https://orcid.org/0000-0002-4936-9824)
- Xuejun Ma (ORCID: https://orcid.org/0000-0001-5891-5260)
- Hongyi Li (ORCID: https://orcid.org/0000-0003-3414-7070)
- Yuxin Wang (ORCID: https://orcid.org/0000-0002-6174-4500)
- Ruiqing Zhang (ORCID: https://orcid.org/0000-0002-5130-3306)
- Xiaona Lv
- Zhiqiang Han (ORCID: https://orcid.org/0000-0001-8414-2046)
Institutions
- Hebei Medical University (CN)
- Hebei North University (CN)
- Chinese Center For Disease Control and Prevention (CN)
- Hebei General Hospital (CN)
- National Institute for Viral Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3389/fmicb.2025.1548965
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79