Identification of causative agents of infective endocarditis by metagenomic next-generation sequencing of resected valves
This study underscores mNGS as a valuable diagnostic tool for detecting IE pathogens, complementing traditional diagnostic methods. The detection of antibiotic resistance genes and multi-locus sequence typing profiles in some samples further demonstrated its utility.
Authors
- Myriam Girard
- Gesuèle Renzi
- Christoph Huber (ORCID: https://orcid.org/0000-0001-9048-849X)
- Nadia Gaïa
- Florian Mauffrey (ORCID: https://orcid.org/0000-0003-4834-7786)
- Yannick Charretier (ORCID: https://orcid.org/0000-0002-8772-0697)
- Truong‐Thanh Pham (ORCID: https://orcid.org/0000-0003-0284-7080)
- Mikaël de Lorenzi-Tognon (ORCID: https://orcid.org/0000-0002-2969-542X)
- Jacques Schrenzel (ORCID: https://orcid.org/0000-0001-5464-7764)
- Vladimir Lazarević (ORCID: https://orcid.org/0000-0002-1782-4423)
Institutions
- University of Geneva (CH)
- University Hospital of Geneva (CH)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3389/fcimb.2025.1532257
- Citations
- 6
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 8.13