3D-Printed Poly (Lactic-Co-Glycolic Acid) and Graphene Oxide Nerve Guidance Conduit with Mesenchymal Stem Cells for Effective Axon Regeneration in a Rat Sciatic Nerve Defect Model
Our novel PLGA/GO NGC, both with and without MSCs, showed results comparable to or greater than the current gold standard, as well as ease of use surgically. With further studies to validate functional recovery, this specific combination of PLGA and GO may provide an effective biomimetic therapy to repair PNIs.
Authors
- Dustin L. Crouch (ORCID: https://orcid.org/0000-0002-9498-4308)
- David E. Anderson (ORCID: https://orcid.org/0000-0003-0745-7591)
- Steven D. Newby
- Thomas Masi (ORCID: https://orcid.org/0000-0001-5328-7250)
- Meaghan E. Harley‐Troxell (ORCID: https://orcid.org/0000-0002-7089-7728)
- Stacy M. Stephenson
- Alisha P. Pedersen
- Madhu Dhar (ORCID: https://orcid.org/0000-0002-0610-5351)
- Eli Christoph (ORCID: https://orcid.org/0009-0007-7545-2473)
Institutions
- University of Tennessee Medical Center (US)
- University of Tennessee at Knoxville (US)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/ijn.s501241
- Citations
- 5
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 4.55