Evaluation of antimicrobial prophylaxis in genital gender affirmation surgery

This study observed an acceptable prevalence of surgical site infections within both 30 days and 6 months of genital gender affirmation surgery. This outcome supports the use of narrow gram-positive and gram-negative coverage (ie, cefazolin) for clean and clean-contaminated procedures without entry into the gastrointestinal (GI) or gastroduodenal (GU) tracts, with the addition of anaerobic coverage (ie, metronidazole) for clean-contaminated procedures with entry into the GI or GU tract, as clinically appropriate options.

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Publication Details

Journal
American Journal of Health-System Pharmacy
Published
2025-03-13
DOI
https://doi.org/10.1093/ajhp/zxaf063
Primary Topic
Female Genital Mutilation/Cutting Issues
Type
article
Field-Weighted Citation Impact
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article

Evaluation of antimicrobial prophylaxis in genital gender affirmation surgery

Monica R. Macik, Andrew C. Lodolo, Mary Soyster, David R. Foster et al.
American Journal of Health-System Pharmacy
Female Genital Mutilation/Cutting Issues
article

Evaluation of antimicrobial prophylaxis in genital gender affirmation surgery

Monica R. Macik, Andrew C. Lodolo, Mary Soyster, David R. Foster, Mary E. Blair, Kerri E. Degenkolb, Taylor Rhew, Joshua D. Roth, Lauren Schmidt
article en

Abstract

This study observed an acceptable prevalence of surgical site infections within both 30 days and 6 months of genital gender affirmation surgery. This outcome supports the use of narrow gram-positive and gram-negative coverage (ie, cefazolin) for clean and clean-contaminated procedures without entry into the gastrointestinal (GI) or gastroduodenal (GU) tracts, with the addition of anaerobic coverage (ie, metronidazole) for clean-contaminated procedures with entry into the GI or GU tract, as clinically appropriate options.

American Journal of Health-System PharmacyVol. 82(8)
Indiana University Health (US), Purdue University West Lafayette (US), Eskenazi Health Foundation (US), Eskenazi Health, Indiana University – Purdue University Indianapolis (US)
Quality Education
Openalex Percentile: Top 93%
Female Genital Mutilation/Cutting Issues
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