Methodological influences on circulating cell-free-mitochondrial and nuclear DNA concentrations in response to chronic stress
ccf-mtDNA can directly and reliably quantified in unpurified plasma samples. However, the ccf-mtDNA levels in plasma samples of healthy subjects are close the LOQ, showing that the assay is not yet suitable for all conditions.
Authors
- Elmo W. I. Neuberger (ORCID: https://orcid.org/0000-0003-2021-6477)
- Benedict Herhaus (ORCID: https://orcid.org/0000-0002-3456-9735)
- Perikles Simon (ORCID: https://orcid.org/0000-0002-7996-4034)
- Katja Petrowski (ORCID: https://orcid.org/0000-0001-7297-2093)
- Carina Daubermann
Institutions
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1007/s11033-025-10369-7
- Citations
- 4
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Universitätsmedizin der Johannes Gutenberg-Universität Mainz