Intrahepatic cholestasis of pregnancy: A case report

Intrahepatic cholestasis of pregnancy is the most common liver disease that occurs exclusively during pregnancy. Its development poses a potential risk to the mother, but especially to the fetus, and requires appropriate management and follow-up. The clinical presentation is characterized by pruritus and elevation of bile acid concentration, but there may be alterations in hepatic biochemical parameters, leading to a thorough differential diagnosis to rule out other liver diseases that may occur during pregnancy. We present the case of a pregnant woman who presented with pruritus since the end of the first trimester with the finding of elevated bile acid concentration in the moderate range and in whom other possible causes of liver involvement were ruled out.

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Publication Details

Journal
World Journal of Advanced Research and Reviews
Published
2025-03-13
DOI
https://doi.org/10.30574/wjarr.2025.25.3.0773
Primary Topic
Drug Transport and Resistance Mechanisms
Type
article
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article

Intrahepatic cholestasis of pregnancy: A case report

Ricardo David Rodriguez Camargo, Fabiola Pérez Miranda, Virginia Luis Fuentes, Vanessa Rocío Villanueva Guerrero et al.
World Journal of Advanced Research and Reviews
Drug Transport and Resistance Mechanisms
article

Intrahepatic cholestasis of pregnancy: A case report

Ricardo David Rodriguez Camargo, Fabiola Pérez Miranda, Virginia Luis Fuentes, Vanessa Rocío Villanueva Guerrero, Fabio David Rodriguez Carrascal, Germán Pertuz Rebolledo
article en

Abstract

Intrahepatic cholestasis of pregnancy is the most common liver disease that occurs exclusively during pregnancy. Its development poses a potential risk to the mother, but especially to the fetus, and requires appropriate management and follow-up. The clinical presentation is characterized by pruritus and elevation of bile acid concentration, but there may be alterations in hepatic biochemical parameters, leading to a thorough differential diagnosis to rule out other liver diseases that may occur during pregnancy. We present the case of a pregnant woman who presented with pruritus since the end of the first trimester with the finding of elevated bile acid concentration in the moderate range and in whom other possible causes of liver involvement were ruled out.

World Journal of Advanced Research and ReviewsVol. 25(3)
Openalex Percentile: Top 93%
Drug Transport and Resistance Mechanisms
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