Comparison of structures and inhibition activities of serine protease inhibitors of Trichinella spiralis and Trichinella pseudospiralis
In this study, the mechanism of enzyme inhibition activity of serpin was studied by means of structural biology and biochemistry comprehensively. These discoveries provide a theoretical foundation for a deeper understanding of the inhibition mechanisms of serpins and for the development of new drugs and vaccines against Trichinella spiralis infection.
Authors
- Bing Zhang (ORCID: https://orcid.org/0000-0001-8556-8049)
- Chen Chen (ORCID: https://orcid.org/0000-0002-7099-7905)
- Ruixue Li (ORCID: https://orcid.org/0000-0002-2523-8416)
Institutions
- Tianjin Medical University (CN)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s13578-025-01375-0
- Citations
- 1
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Tianjin-Science and Technology Correspondent Project