High Systemic Disease Risk and Therapeutic Delays in Plaque Psoriasis: A Retrospective Analysis of Apremilast Use in the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR)

Our data indicate that patients with plaque psoriasis prescribed apremilast in UK clinical practice have a high comorbidity burden and long-term, moderate-to-severe disease with special-site involvement, uncontrolled by systemic therapy, and which had a large detrimental impact on their QoL. These data highlight the need for timely treatment with appropriate therapy following diagnosis.

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Publication Details

Journal
Dermatology and Therapy
Published
2025-03-13
DOI
https://doi.org/10.1007/s13555-025-01358-6
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

High Systemic Disease Risk and Therapeutic Delays in Plaque Psoriasis: A Retrospective Analysis of Apremilast Use in the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR)

Vaiva Gerasimaviciute, Kave Shams, David Neasham, Andrew W. Taylor et al.
Dermatology and Therapy
Psoriasis: Treatment and Pathogenesis
article

High Systemic Disease Risk and Therapeutic Delays in Plaque Psoriasis: A Retrospective Analysis of Apremilast Use in the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR)

Vaiva Gerasimaviciute, Kave Shams, David Neasham, Andrew W. Taylor, Myriam Cordey, Anouchka Seesaghur, Kathy Tran, Jennifer Montgomery, J. E. Morley
article en

Abstract

Our data indicate that patients with plaque psoriasis prescribed apremilast in UK clinical practice have a high comorbidity burden and long-term, moderate-to-severe disease with special-site involvement, uncontrolled by systemic therapy, and which had a large detrimental impact on their QoL. These data highlight the need for timely treatment with appropriate therapy following diagnosis.

Dermatology and TherapyVol. 15(4)
University of Leeds (GB), Amgen (United States) (US), Chapel Allerton Hospital (GB), Amgen (United Kingdom) (GB)
Good health and well-being
Openalex Percentile: Top 95%
Psoriasis: Treatment and Pathogenesis
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High Systemic Disease Risk and Therapeutic Delays in Plaque Psoriasis: A Retrospective Analysis of Apremilast Use in the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR) — Vaiva Gerasimaviciute, Kave Shams, et al. · Dermatology and Therapy (2025) | TGRS Research Map | TGRS