A real-world study of the efficacy of second-line treatment of unresectable hepatocellular carcinoma with esophagogastric varices after progression on first-line lenvatinib combined with PD-1 inhibitor
The second-line treatment of unresectable hepatocellular carcinoma with esophagogastric varices after progression on first-line lenvatinib combined with PD-1 inhibitor is effective. Regorafenib or apatinib combined with PD-1 inhibitor might be the preferred options.
Authors
- Saifeng Li
- Long Feng (ORCID: https://orcid.org/0000-0001-7398-9444)
- Wen-wu Huang (ORCID: https://orcid.org/0009-0001-6761-2314)
- Fengming Yi (ORCID: https://orcid.org/0000-0002-9417-644X)
- Wen Qin (ORCID: https://orcid.org/0000-0001-8966-7722)
- Zhenye Qiu
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s12957-025-03742-0
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Jiangxi Provincial Department of Science and Technology