Mediating Role of Blood Metabolites in the Relationship Between Immune Cell Traits and Heart Failure: A Mendelian Randomization and Mediation Analysis
These findings underscore the importance of HLA DR on CD33dim HLA DR+ CD11b+ in the development of HF, with Octadecanedioate levels acting as a possible mediator in this pathway.
Authors
- Yi Liu (ORCID: https://orcid.org/0000-0003-4462-3210)
- Yu Cao (ORCID: https://orcid.org/0000-0003-4715-7331)
- Chenfu Shen (ORCID: https://orcid.org/0000-0003-4632-1347)
Institutions
- Central South University (CN)
- Sichuan University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1161/jaha.124.037265
- Citations
- 3
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 2.39