Musculoskeletal disease in acromegaly—a population-based registry study
In acromegaly, severe osteoarthritis involving multiple joints develops even before acromegaly diagnosis and continues to progress over time after acromegaly treatment. Furthermore, acromegaly imposes an increased risk of medically treated osteoporosis, musculoskeletal surgery-particularly joint replacement surgery-, surgical complications, and the necessity of analgesic medication. Our findings warrant further research into the management of musculoskeletal disease in acromegaly.
Authors
- Mai Christiansen Arlien-Søborg (ORCID: https://orcid.org/0000-0001-8424-558X)
- Marianne Andersen (ORCID: https://orcid.org/0000-0002-4603-9504)
- Christian Rosendal (ORCID: https://orcid.org/0000-0003-1333-4387)
- Claus Larsen Feltoft
- Jens Otto Lunde Jørgensen (ORCID: https://orcid.org/0000-0001-7408-1526)
- Eigil Husted Nielsen (ORCID: https://orcid.org/0000-0002-7990-3557)
- Åse Krogh Rasmussen (ORCID: https://orcid.org/0000-0002-9729-4767)
- Jakob Dal
Institutions
- Ipsen (France) (FR)
- Pfizer (United Kingdom) (GB)
- Aalborg University Hospital (DK)
- Odense University Hospital (DK)
- Herlev Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
- Rigshospitalet (DK)
- Steno Diabetes Center North Jutland (DK)
- Aalborg University (DK)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1093/ejendo/lvaf047
- Citations
- 6
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.77
Funders
- Pfizer
- Ipsen