Clinical outcomes and molecular characteristics of lung-only and liver-only metastatic pancreatic cancer: results from a real-world evidence database
Patients with lung-only mPDAC demonstrate an improved prognosis relative to those with liver-only mPDAC. Responses to chemotherapy do not explain these differences. Organotropic metastatic tumor diversity is mirrored at the molecular level in PDAC.
Authors
- Arsen Osipov (ORCID: https://orcid.org/0000-0002-9000-7040)
- Rachna T. Shroff (ORCID: https://orcid.org/0000-0003-0066-2672)
- Michael J. Pishvaian (ORCID: https://orcid.org/0000-0002-1165-9041)
- Andrew Hendifar (ORCID: https://orcid.org/0000-0002-2079-9177)
- Edik M. Blais (ORCID: https://orcid.org/0000-0001-5609-3849)
- John Davelaar (ORCID: https://orcid.org/0000-0002-2426-6749)
- Angela Minasyan (ORCID: https://orcid.org/0000-0003-4453-0153)
- Matthew Ebia (ORCID: https://orcid.org/0000-0001-7159-1926)
- Patricia DeArbeloa (ORCID: https://orcid.org/0000-0002-6597-9104)
- Abrahm Levi (ORCID: https://orcid.org/0009-0005-3074-6166)
- Lei Zheng (ORCID: https://orcid.org/0000-0003-4788-597X)
- Raymond Wadlow (ORCID: https://orcid.org/0000-0003-1959-5406)
- Lynn M. Matrisian (ORCID: https://orcid.org/0000-0002-5631-2826)
- Gillian Gresham (ORCID: https://orcid.org/0000-0001-7142-1230)
- Jennifer Chuy (ORCID: https://orcid.org/0000-0002-0279-7960)
- Nima Nikravesh
- Jun Gong (ORCID: https://orcid.org/0000-0001-8713-1406)
- Emmanuel Petricoin
Institutions
- Cedars-Sinai Medical Center (US)
- University of Arizona (US)
- Johns Hopkins University (US)
- The University of Texas at San Antonio Health Science Center (US)
- Johns Hopkins Medicine (US)
- Inova Fairfax Hospital (US)
- Pancreatic Cancer Action Network (US)
- NYU Langone Health (US)
- Sidney Kimmel Comprehensive Cancer Center (US)
Publication Details
- Journal
- The Oncologist
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1093/oncolo/oyaf007
- Citations
- 5
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 5.23
Funders
- Conquer Cancer Foundation
- American Society of Clinical Oncology
- National Institutes of Health