Cerebral Hemodynamic Impairment and Cognitive Dysfunction in <i>APOE4</i> Carriers With Asymptomatic Carotid Artery Stenosis/Occlusion
<i>APOE4</i> may confer an increased risk of decreased cerebral blood flow accompanied by memory impairment in asymptomatic carotid artery stenosis or occlusion consistent with our experimental study. <i>APOE</i> genotyping in such subjects may be useful for early detection of disease severity.
Authors
- Masafumi Ihara (ORCID: https://orcid.org/0000-0002-7102-4048)
- Yoshinori KAKINO (ORCID: https://orcid.org/0000-0002-1159-8680)
- Yorito Hattori (ORCID: https://orcid.org/0000-0002-1495-4433)
- Hidehiro Iida
- Kunihiro Nishimura (ORCID: https://orcid.org/0000-0002-0639-0949)
- Soshiro Ogata (ORCID: https://orcid.org/0000-0002-0100-376X)
- Yuriko Nakaoku (ORCID: https://orcid.org/0000-0002-3100-574X)
Institutions
- University of Turku (FI)
- Turku University Hospital (FI)
- National Cerebral and Cardiovascular Center (JP)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1161/jaha.124.039210
- Citations
- 1
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.84