Effect of isavuconazole on the concentration of tacrolimus in a patient with genotype CYP3A5*1/*3: a case report
In the early stages of ISCZ treatment, the blood TAC concentration is higher, and CYP3A5 polymorphisms may partially explain the extent of this interaction. We recommend more careful monitoring of TAC and serum creatinine levels for approximately one week after ISCZ administration.
Authors
- Masafumi Kikuchi (ORCID: https://orcid.org/0000-0003-2148-6129)
- S. Sakamoto (ORCID: https://orcid.org/0000-0002-3394-2825)
- Masahide Takeda (ORCID: https://orcid.org/0000-0002-7028-7073)
- Yumiko Akamine (ORCID: https://orcid.org/0000-0002-1346-757X)
- Hayato Yokota (ORCID: https://orcid.org/0000-0003-1389-435X)
- Katsutoshi Nakayama
- Hiromitsu Hatakeyama (ORCID: https://orcid.org/0000-0002-6068-5289)
- Kazuhiro Sato
- Mitsuru Saito (ORCID: https://orcid.org/0000-0003-1653-4309)
- H.‐Matsuo Kagaya
Institutions
- Akita University (JP)
- Akita University Hospital (JP)
Publication Details
- Journal
- Journal of Pharmaceutical Health Care and Sciences
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s40780-025-00427-4
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 2.79