Recent Neuropathology Concepts
The last session of the 2024 European Society of Toxicologic Pathology Congress was dedicated to recent neuro concepts, encompassing various topics including artificial intelligence (AI) applied to toxicologic pathology, new technologies for visualization and/or analysis of tissues, as well as specific case reports. Four presentations detailed the role of AI and computational pathology for toxicologic pathologists, usage of cryofluorescent tomography in neuropathology, blood-brain barrier organoids in early drug screening, and spatial transcriptomics in toxicologic pathology. In addition, there were two short presentations about a spontaneous brain lesion in Beagle dogs as well as central nervous system lesions related to adeno-associated virus vectors administration in various preclinical species. This session underscored the current and prospective impact of emerging technologies on drug screening and development.
Authors
- Ingrid D. Pardo (ORCID: https://orcid.org/0000-0002-3517-3804)
- Kerstin Hahn (ORCID: https://orcid.org/0000-0003-3602-4234)
- Julie Boisclair (ORCID: https://orcid.org/0000-0002-3699-5631)
- Pierre Maliver (ORCID: https://orcid.org/0000-0003-1061-6063)
- Luisa Bell
- Elizabeth J. Galbreath (ORCID: https://orcid.org/0000-0003-0162-8329)
- Benedek Pesti (ORCID: https://orcid.org/0000-0002-9055-6699)
- Stefanie Arms (ORCID: https://orcid.org/0009-0002-9434-6442)
Institutions
- Roche (Switzerland) (CH)
- University of Bern (CH)
- Novartis (Switzerland) (CH)
- Biogen (United States) (US)
- Boehringer Ingelheim (Germany) (DE)
- Experimental Pathology Laboratories (US)
Publication Details
- Journal
- Toxicologic Pathology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1177/01926233251320056
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00