Flagellar Assembly Factor <scp>FliW2</scp> De‐Represses <i>Helicobacter pylori</i><scp>FlaA</scp>‐Mediated Motility by Allosteric Obstruction of Global Regulator <scp>CsrA</scp>
Our data points to novel regulatory roles that the H. pylori flagellar assembly factor FliW2 has in obstructing CsrA activity, and thus FliW2 may indirectly antagonize CsrA's regulation of flaA mRNA processing and translation. Our findings reveal a new regulatory mechanism of flagellar motility in H. pylori.
Authors
- Pei‐Jane Tsai (ORCID: https://orcid.org/0000-0001-9938-3299)
- Jenn‐Wei Chen (ORCID: https://orcid.org/0000-0002-5433-5178)
- Benjamin Dickins (ORCID: https://orcid.org/0000-0002-0866-6232)
- Marcia Shu‐Wei Su (ORCID: https://orcid.org/0000-0002-5054-7800)
- Shuying Wang (ORCID: https://orcid.org/0000-0003-3339-8070)
- Jiunn‐Jong Wu
- Wei‐Jiun Tsai
- Yueh‐Lin Chen
- Fang Yie Kiang
Institutions
- Asia University (TW)
- National Yang Ming Chiao Tung University (TW)
- China Medical University (TW)
- China Medical University Hospital (TW)
- Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
- Nottingham Trent University (GB)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Helicobacter
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/hel.70019
- Citations
- 2
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Shanghai Educational Development Foundation
- National Science and Technology Council