Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy
This study underscores the dual importance of both cellular composition and spatial organization in steering clinical response to immunotherapy.
Authors
- Ziena Abdulrahman (ORCID: https://orcid.org/0000-0001-9079-0293)
- Roderick C. Slieker (ORCID: https://orcid.org/0000-0003-0961-9152)
- Sjoerd H. van der Burg (ORCID: https://orcid.org/0000-0002-6556-0354)
- Mariëtte I.E. van Poelgeest (ORCID: https://orcid.org/0000-0001-5432-5001)
- Marij J.P. Welters (ORCID: https://orcid.org/0000-0002-9809-8266)
- Daniel McGuire
Institutions
- Leiden University Medical Center (NL)
- Nanostring Technologies (United States) (US)
- Oncode Institute (NL)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1136/jitc-2024-011308
- Citations
- 14
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 11.16
Funders
- Leids Universitair Medisch Centrum
- Oncode Institute