Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence
These findings underscore the critical role of Gfa1 in fungal pathogenicity and suggest its potential as a therapeutic target for combating A. fumigatus infections.
Authors
- Sayed Usman
- Qijian Qin
- Wenxia Fang (ORCID: https://orcid.org/0000-0001-8055-2072)
- Chukwuemeka Samson Ahamefule (ORCID: https://orcid.org/0000-0001-7374-1641)
- Pingzhen Wei
- Daan M. F. van Aalten (ORCID: https://orcid.org/0000-0002-1499-6908)
- Kaizhou Yan (ORCID: https://orcid.org/0000-0002-3798-6083)
- Cheng Jin (ORCID: https://orcid.org/0000-0002-1514-6374)
- Bin Wang (ORCID: https://orcid.org/0000-0001-7665-6290)
Institutions
- University of Dundee (GB)
- Chinese Academy of Sciences (CN)
- Aarhus University (DK)
- Guangxi Academy of Agricultural Science (CN)
- Institute of Microbiology (CN)
- Guangxi Academy of Sciences (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s12915-025-02184-0
- Citations
- 1
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Wellcome Trust
- Strong
- National Natural Science Foundation of China
- Novo Nordisk
- Novo Nordisk Fonden
- Medical Research Council