Rare but specific: 5-bp composite motifs define SMAD binding in BMP signaling
Deviations from these minimal requirements prevent transcription and underline the need for co-transcription factors to achieve gene activation.
Authors
- Paul‐Lennard Mendez (ORCID: https://orcid.org/0000-0003-2025-7981)
- Su-Il Do
- Rebeca A. Mees (ORCID: https://orcid.org/0000-0002-3292-4924)
- Jerome Jatzlau (ORCID: https://orcid.org/0000-0002-1757-0267)
- Rameez Jabeer Khan (ORCID: https://orcid.org/0000-0002-0997-0535)
- Pau Martín-Malpartida (ORCID: https://orcid.org/0000-0001-5867-5535)
- Lukas Maas (ORCID: https://orcid.org/0000-0002-5830-6710)
- María Jesús Macías (ORCID: https://orcid.org/0000-0002-6915-963X)
- Lidia Ruíz (ORCID: https://orcid.org/0000-0002-8918-9158)
- Petra Knaus
Institutions
- Institute for Research in Biomedicine (ES)
- Freie Universität Berlin (DE)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s12915-025-02183-1
- Citations
- 3
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Deutsche Forschungsgemeinschaft
- Einstein Stiftung Berlin
- Freie Universität Berlin
- Agència de Gestió d'Ajuts Universitaris i de Recerca