Treatment Efficacy of Theophylline in <scp>ADCY5</scp>‐Related Dyskinesia: A Retrospective Case Series Study
Theophylline shows substantial promise as a treatment option for ADCY5-related dyskinesia, improving various aspects of patients' quality of life and movement disorder symptoms. Further research is needed to optimize dosing, to understand long-term effects, and to explore combinational drug therapies. Despite the small cohort size and the retrospective nature of this study, the results support theophylline administration to decrease dyskinetic movements and enhance overall quality of life in patients. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Frank Hause (ORCID: https://orcid.org/0000-0002-6879-6944)
- Andreas Merkenschlager (ORCID: https://orcid.org/0000-0001-9959-2306)
- Andrea Sinz (ORCID: https://orcid.org/0000-0003-1521-4899)
- Dirk Taenzler
Institutions
- Martin Luther University Halle-Wittenberg (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1002/mds.30170
- Citations
- 7
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 9.72
Funders
- Deutsche Forschungsgemeinschaft