Circ-AARS plays an important role during the odontogenic differentiation of dental pulp stem cells by modulating miR-24-3p/KLF6 expression
The present study showed that circ-AARS can promote the odontoblastic differentiation of DPSCs by increasing KLF6 expression and sponging miR-24-3p. Taken together, the results indicate that circ-AARS may be a potential positive regulator of odontoblastic differentiation of DPSCs.
Authors
- Jiaxin Zhou (ORCID: https://orcid.org/0000-0002-5172-3466)
- Mingming Jin (ORCID: https://orcid.org/0000-0003-3574-2410)
- Meizhi Sui
- Tao Jiang (ORCID: https://orcid.org/0000-0002-0469-6944)
- Zian Xiao
- Jiaxuan Lyu
- Qian Liao
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Ninth People's Hospital (CN)
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s13287-025-04239-z
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00