EBV enhances immunotherapy sensitivity in intrahepatic cholangiocarcinoma through cGAS-STING pathway activation

The established EBV-positive ICC cell lines revealed enhanced immunogenicity driven by cGAS-STING pathway activation, providing valuable models for future research and insights into the mechanisms of improved immunotherapy sensitivity in EBVaICC.

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Publication Details

Journal
Hepatology Communications
Published
2025-03-13
DOI
https://doi.org/10.1097/hc9.0000000000000674
Primary Topic
interferon and immune responses
Type
article
Field-Weighted Citation Impact
0.00
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article

EBV enhances immunotherapy sensitivity in intrahepatic cholangiocarcinoma through cGAS-STING pathway activation

Guifang Guo, Lingli Huang, Yuchen Cai, Silan Huang et al.
1 links
Hepatology Communications
interferon and immune responses
article

EBV enhances immunotherapy sensitivity in intrahepatic cholangiocarcinoma through cGAS-STING pathway activation

Guifang Guo, Lingli Huang, Yuchen Cai, Silan Huang, Qian Zhong, Kejia Yang
article en

Abstract

The established EBV-positive ICC cell lines revealed enhanced immunogenicity driven by cGAS-STING pathway activation, providing valuable models for future research and insights into the mechanisms of improved immunotherapy sensitivity in EBVaICC.

Hepatology CommunicationsVol. 9(4)
Sun Yat-sen University (CN), Sun Yat-sen University Cancer Center (CN)
Good health and well-being
Openalex Percentile: Top 95%
interferon and immune responses
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