Liver function estimation using multiphase hepatic CT: diagnostic performance of iodine-uptake and volumetric parameters
Question Despite the widespread use of multiphase CT in patients with hepatobiliary diseases, its potential role in assessing liver function has been scarcely evaluated. Findings Iodine washout rate (IWR), liver volume indexed by body surface area, and spleen volume indexed by body surface area were independent predictors for severe liver dysfunction. Clinical relevance Combined IWR and hepatosplenic volumetry on routine hepatic CT may help assess hepatic function for optimizing treatment strategies and predicting patient prognosis.
Authors
- Masafumi Kidoh (ORCID: https://orcid.org/0000-0002-9589-7054)
- Ryota Harai
- Toshinori Hirai (ORCID: https://orcid.org/0000-0003-1480-2197)
- Takeshi Nakaura (ORCID: https://orcid.org/0000-0002-9010-0341)
- Narumi Taguchi (ORCID: https://orcid.org/0000-0002-0406-9887)
- Koji Ogasawara
- Yasunori Nagayama (ORCID: https://orcid.org/0000-0003-3280-7346)
- Shinya Shiraishi (ORCID: https://orcid.org/0000-0002-1165-9607)
- Seitaro Oda (ORCID: https://orcid.org/0000-0002-0609-2191)
- Yasuhiro Yokota (ORCID: https://orcid.org/0000-0001-7186-7785)
- Ryuya Yoshida
- Masamichi Hokamura
- T Osaki
Institutions
- Kumamoto University (JP)
Publication Details
- Journal
- European Radiology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1007/s00330-025-11497-1
- Citations
- 5
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 6.61