Inflammatory and Humoral Immune Responses to Commercial Autogenous Salmonella Bacterin Vaccines in Light-Brown Leghorn Pullets: Primary and Secondary Vaccine Responses
These commercial-killed <i>Salmonella</i> vaccines, when prepared in water-oil-water emulsions, stimulated prolonged innate and T helper (Th) 17-type inflammatory responses at the injection site and produced a classic systemic humoral immune response after a second vaccination. Further research is needed to determine if extended inflammation influences adaptive immune responses in eliminating <i>Salmonella</i> infection.
Authors
- Gisela F. Erf (ORCID: https://orcid.org/0000-0003-2106-3484)
- Chrysta N. Beck (ORCID: https://orcid.org/0009-0006-3205-1285)
- Jossie M. Santamaria (ORCID: https://orcid.org/0009-0009-8705-5146)
Institutions
- University of Arkansas System (US)
Publication Details
- Journal
- Vaccines
- Published
- 2025-03-13
- DOI
- https://doi.org/10.3390/vaccines13030311
- Citations
- 2
- Primary Topic
- Salmonella and Campylobacter epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.32