Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinoma
Our findings illuminate the heterogeneity of the complex TME in CSCC and offer evidence supporting PCLAF<sup>+</sup> TAEpis as a promising therapeutic target.
Authors
- Qitai Zhao (ORCID: https://orcid.org/0000-0003-4023-2060)
- Mei‐Mei Gao (ORCID: https://orcid.org/0000-0002-2213-9842)
- Juanhua Li
- Fang Ren (ORCID: https://orcid.org/0000-0002-1581-6593)
- Yanmei Cheng
- Xia Li (ORCID: https://orcid.org/0000-0001-8812-5788)
- Junqi Liu (ORCID: https://orcid.org/0000-0002-6015-1033)
- Hao Gu (ORCID: https://orcid.org/0000-0003-3038-9689)
- Mingliang Fan (ORCID: https://orcid.org/0009-0005-4183-4559)
- Jiaqin Yan
- Yanyan Jia (ORCID: https://orcid.org/0000-0002-1051-035X)
- Mei Ji (ORCID: https://orcid.org/0000-0002-5747-0201)
- Chenyin Wang (ORCID: https://orcid.org/0000-0002-4963-777X)
- Huirong Shi (ORCID: https://orcid.org/0000-0002-6751-2858)
- Binhui Wang (ORCID: https://orcid.org/0000-0002-7803-1785)
- Zhao Zhao (ORCID: https://orcid.org/0009-0001-4958-5105)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s12935-025-03725-x
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09