Histopathological and Clinical-Genetic Analysis of Corneal Specimens in Maroteaux–Lamy Syndrome
The study highlights the alterations in various corneal layers, which have seldom been reported on Maroteaux-Lamy syndrome. Nonetheless, the GAG deposits identified and the changes in Bowman layer align with the literature. PK temporarily improved corneal clarity. However, long-term visual outcomes were poor because of optic nerve damage. Early diagnosis and multidisciplinary management are essential to improve outcomes.
Authors
- José Manuel Lopes (ORCID: https://orcid.org/0000-0001-8597-3474)
- Elisa Leão Teles (ORCID: https://orcid.org/0000-0002-3011-0249)
- Ana Faria Pereira (ORCID: https://orcid.org/0000-0001-7770-5146)
- Raúl Moreira
- Augusto Magalhães (ORCID: https://orcid.org/0000-0003-1433-0708)
- Sofia Pedrosa
Institutions
- Universidade do Porto (PT)
- Hospital de São João (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Cornea
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1097/ico.0000000000003855
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00