Telomere length and telomerase reverse transcriptase gene polymorphism as potential markers of complete chimerism and GvHD development after allogeneic haematopoietic stem cell transplantation
Our results suggest that recipient allele TERTp rs2853669 T is a marker of unfavourable outcome in the context of aGvHD. Shorter TL in donors could be associated with later achievement of complete chimerism.
Authors
- Barbara Nasiłowska‐Adamska (ORCID: https://orcid.org/0000-0002-1795-8034)
- Wojciech Fidyk (ORCID: https://orcid.org/0000-0002-5953-7131)
- Małgorzata Sobczyk‐Kruszelnicka (ORCID: https://orcid.org/0000-0002-2007-7609)
- Jagoda Siemaszko (ORCID: https://orcid.org/0000-0002-4440-1709)
- Sebastian Giebel (ORCID: https://orcid.org/0000-0002-4827-4401)
- Piotr Łacina (ORCID: https://orcid.org/0000-0002-9659-9403)
- Marta Dratwa (ORCID: https://orcid.org/0000-0003-4077-7538)
- Grzegorz Władysław Basak (ORCID: https://orcid.org/0000-0003-3858-8180)
- Maria Bieniaszewska (ORCID: https://orcid.org/0000-0002-5704-0244)
- Patrycja Skowrońska
- Iwona Solarska (ORCID: https://orcid.org/0000-0002-9748-4894)
- Barbara Wysoczańska (ORCID: https://orcid.org/0000-0002-7554-3208)
- Katarzyna Bogunia‐Kubik (ORCID: https://orcid.org/0000-0001-9744-0376)
- Agnieszka Tomaszewska (ORCID: https://orcid.org/0000-0002-3211-5713)
- Dorota Kilinska
Institutions
- Medical University of Warsaw (PL)
- Instytut Hematologii i Transfuzjologi (PL)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Ludwik Hirszfeld Institute of Immunology and Experimental Therapy (PL)
- Gdańsk Medical University (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1007/s00432-025-06160-7
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Narodowym Centrum Nauki