Postpartum Hemorrhage-Induced Acute Kidney Injury Following Obstetric Hysterectomy: A Case Report

Pregnancy-related acute kidney injury (AKI) is rare, with hemorrhage and sepsis being its most common causes when it occurs. A 27-year-old multiparous woman presented to our Emergency Department at 37 weeks of gestation at the end of the second stage of labor. Vaginal delivery was completed without complications, however, immediately postpartum, inadequate uterine contraction led to hemodynamic instability. Conservative measures failed to control the hemorrhage, leading to the decision to perform an obstetric hysterectomy to restore stability. The surgical procedure was successful, however, progressive renal dysfunction with rising creatinine levels occurred postoperatively, prompting the initiation of hemodialysis sessions, which continued for six days until the full restoration of kidney function. This report describes the occurrence of AKI as a result of postpartum hemorrhage following vaginal delivery and outlines its key risk factors, in addition to diagnosis and treatment options. Proper understanding of these factors can significantly contribute to ensuring maternal health and optimizing perinatal outcomes.

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Journal
Cureus
Published
2025-03-13
DOI
https://doi.org/10.7759/cureus.80516
Primary Topic
Maternal and fetal healthcare
Type
article
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article

Postpartum Hemorrhage-Induced Acute Kidney Injury Following Obstetric Hysterectomy: A Case Report

Emmanouil M Xydias, Ioannis Paraoulakis, Apostolos C Ziogas, Anna Thanasa et al.
Cureus
Maternal and fetal healthcare
article

Postpartum Hemorrhage-Induced Acute Kidney Injury Following Obstetric Hysterectomy: A Case Report

Emmanouil M Xydias, Ioannis Paraoulakis, Apostolos C Ziogas, Anna Thanasa, Evangelos Kamaretsos, Efthymia Thanasa, Gerasimos Kontogeorgis, Ioannis Thanasas
article en

Abstract

Pregnancy-related acute kidney injury (AKI) is rare, with hemorrhage and sepsis being its most common causes when it occurs. A 27-year-old multiparous woman presented to our Emergency Department at 37 weeks of gestation at the end of the second stage of labor. Vaginal delivery was completed without complications, however, immediately postpartum, inadequate uterine contraction led to hemodynamic instability. Conservative measures failed to control the hemorrhage, leading to the decision to perform an obstetric hysterectomy to restore stability. The surgical procedure was successful, however, progressive renal dysfunction with rising creatinine levels occurred postoperatively, prompting the initiation of hemodialysis sessions, which continued for six days until the full restoration of kidney function. This report describes the occurrence of AKI as a result of postpartum hemorrhage following vaginal delivery and outlines its key risk factors, in addition to diagnosis and treatment options. Proper understanding of these factors can significantly contribute to ensuring maternal health and optimizing perinatal outcomes.

CureusVol. 17(3)
University of Thessaly (GR), BioClinica (United States) (US), National and Kapodistrian University of Athens (GR), Aristotle University of Thessaloniki (GR), University Hospital of Larissa (GR), e-Trikala (Greece) (GR)
Good health and well-being
Openalex Percentile: Top 94%
Maternal and fetal healthcare
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Postpartum Hemorrhage-Induced Acute Kidney Injury Following Obstetric Hysterectomy: A Case Report — Emmanouil M Xydias, Ioannis Paraoulakis, et al. · Cureus (2025) | TGRS Research Map | TGRS