Impact of comorbidities on management and outcomes of patients weaning from invasive mechanical ventilation: insights from the WEAN SAFE study
Most patients weaning from invasive ventilation have comorbidities, which are associated with higher weaning failure risk and worse outcomes. The adverse impact of comorbidities on the weaning outcomes and of the process are not explained by a less aggressive approach to weaning.
Authors
- Andrew J. Simpkin (ORCID: https://orcid.org/0000-0002-4975-444X)
- Bairbre McNicholas (ORCID: https://orcid.org/0000-0001-9524-4021)
- Leo Heunks (ORCID: https://orcid.org/0000-0003-3196-4665)
- Tài Pham (ORCID: https://orcid.org/0000-0002-4373-0711)
- Laurent Brochard
- John G. Laffey (ORCID: https://orcid.org/0000-0002-1246-9573)
- Giacomo Bellani
- Rionach Sheerin
- Omid Khazaei
Institutions
- Université Paris-Sud (FR)
- St. Michael's Hospital (CA)
- Radboud University Nijmegen (NL)
- Inserm (FR)
- University of Toronto (CA)
- Ollscoil na Gaillimhe – University of Galway (IE)
- University of Trento (IT)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Université Paris-Saclay (FR)
- University Hospital Galway (IE)
- Radboud University Medical Center (NL)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Saolta University Health Care Group (IE)
- Bicêtre Hospital (FR)
- Unity Health Toronto
Publication Details
- Journal
- Critical Care
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1186/s13054-025-05341-7
- Citations
- 10
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 15.18
Funders
- European Respiratory Society
- Health Research Board
- European Society of Intensive Care Medicine