Acute toxicity and quality of life after margin reduction using a sub-fractionation workflow for stereotactic radiotherapy of localized prostate cancer on a 1.5 Tesla MR-linac
Margin reduction below 5 mm did not seem to reduce acute toxicity after radiotherapy with a stereotactic body radiotherapy (SBRT) treatment schedule in localized prostate cancer. The introduction of real-time comprehensive motion management with prostate gating could further lower GU and GI toxicity and ameliorate treatment related quality of life.
Authors
- Tariq A. Lalmahomed (ORCID: https://orcid.org/0000-0002-9007-5713)
- Eline N. de Groot-van Breugel
- Harm H.E. van Melick (ORCID: https://orcid.org/0000-0001-9285-0632)
- Louk M.W. Snoeren
- Jochem Hes
- Johannes C.J. de Boer
- T. Willigenburg (ORCID: https://orcid.org/0000-0002-4813-6295)
- Jochem R.N. van der Voort van Zyp
- Helena M. Verkooijen (ORCID: https://orcid.org/0000-0001-9480-1623)
- Sandrine M.G. van de Pol
Institutions
- University Medical Center Utrecht (NL)
- St. Antonius Ziekenhuis (NL)
- Oncode Institute (NL)
- Cancer Genomics Centre (NL)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1016/j.radonc.2025.110845
- Citations
- 1
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52