The comparison of gut microbiota between different types of epilepsy in children
Though, there were no statistically significant differences in gut microbiota between the different types of epilepsy, the gut microbiota of children with epilepsy significantly differed from that of healthy controls. The increased abundance of Escherichia/Shigella may lead to the worsening of clinical phenotypes and poor prognosis, and it could be a candidate biomarker to identify the focal epilepsy or even non-benign childhood epilepsy with centrotemporal spikes, potentially providing new therapeutic targets for the future.
Authors
- Xiongfeng Pan (ORCID: https://orcid.org/0000-0002-3443-6465)
- Jiajia You (ORCID: https://orcid.org/0009-0000-0055-4124)
- Liwen Wu (ORCID: https://orcid.org/0000-0003-1031-7899)
- Changci Zhou
- Zhenghui Xiao
- Jun Qiu (ORCID: https://orcid.org/0000-0001-6123-8766)
- Ningning Hu
- Siwei Fang
Institutions
- Central South University (CN)
- Second People Hospital of Hunan (CN)
- Hunan Children's Hospital (CN)
- Hunan Institute of Mental Health (CN)
- University of South China (CN)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1186/s12934-025-02684-2
- Citations
- 2
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.33