Synthesis of Agcl Cube/Porous Carbon Nanotubes Composition for Nonenzymatic Electrochemically Sensing H <sub>2</sub> O <sub>2</sub> Released from Cancer Cells
The abnormal expression of hydrogen peroxide (H 2 O 2 ) in living cells is closely related to the occurrence and development of tumor diseases. It is a kind potential marker for tumor diagnosis and treatment of tumor diseases. Therefore, it is very meaningful to develop high selective and sensitive method for real‐time detecting H 2 O 2 released from cancer cells. Herein, an AgCl cube/porous carbon nanotube composite nanomaterials was successfully fabricated and employed to construct a non‐enzymatic electrochemical H 2 O 2 sensor. Test results showed that the proposed sensor displayed the high sensitivity with the detection limit of 5.3 × 10 −9 mol/L (S/N = 3). Importantly, it can accurately analyze H 2 O 2 in milk samples and achieve real‐time determination of H 2 O 2 secreted from living cancer cells. In addition, the established sensor exhibited good stability and anti‐interference ability. This strategy offers a potential way to diagnose tumor diseases.
Authors
- Yongxiang Su (ORCID: https://orcid.org/0000-0002-8057-8747)
- Hongyan Wang (ORCID: https://orcid.org/0000-0002-1754-4018)
- Yilin Wu (ORCID: https://orcid.org/0000-0002-3549-6259)
- Rongli Jiang (ORCID: https://orcid.org/0000-0003-0136-3236)
- Yan Wang (ORCID: https://orcid.org/0000-0002-3341-1469)
- Na Zhang (ORCID: https://orcid.org/0000-0002-9097-9587)
- Keying Zhang (ORCID: https://orcid.org/0000-0002-7888-7938)
- X. Xie (ORCID: https://orcid.org/0009-0006-7698-3906)
Institutions
- China University of Mining and Technology (CN)
- Soochow University (CN)
- Southeast University (CN)
Publication Details
- Journal
- Electroanalysis
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/elan.12039
- Citations
- 1
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 0.73
Funders
- Natural Science Foundation of Anhui Province