Characteristics of RET gene mutations in Vietnamese medullary thyroid carcinoma patients: a single-center analysis
Our results provided the first comprehensive analysis of RET mutations in Vietnamese MTC patients. The most frequent mutation was p.M918T, followed by p.C634R and p.C618R. Mutations in these three exons were linked to specific histopathological features. Information on mutational profiles of patients with MTC will further aid in the development of targeted therapeutics to ensure effective disease management.
Authors
- Thao Thi Thu Luu (ORCID: https://orcid.org/0009-0006-8369-7676)
- Hieu Trong Ngo
- Hoàng Anh Vũ (ORCID: https://orcid.org/0000-0003-4232-6001)
- Dat Quoc Ngo (ORCID: https://orcid.org/0000-0003-1461-0216)
- Anh Tu Thai
- Quốc Thắng Phạm (ORCID: https://orcid.org/0000-0001-8787-367X)
- Van Hung Pham (ORCID: https://orcid.org/0009-0007-0289-9952)
- T. P. Dang
- Minh Nguyen
- Nha Dao Thi Minh
Institutions
- University of Medicine and Pharmacy at Ho Chi Minh City (VN)
- University Medical Center HCMC (VN)
- HCMC Hospital of Dermato Venereology (VN)
Publication Details
- Journal
- Journal of Pathology and Translational Medicine
- Published
- 2025-03-14
- DOI
- https://doi.org/10.4132/jptm.2025.01.18
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00