Multiomics Identifies Potential Molecular Profiles Associated With Outcomes After BRAF-Targeted Therapy in Patients With BRAF V600E-Mutated Advanced Solid Tumors

Using a multiomic approach, we identified molecular alterations associated with treatment outcomes. The potential of analyzing multiomic data is promising and should be prioritized in translational cancer research to uncover the full potential within precision oncology.

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Publication Details

Journal
JCO Precision Oncology
Published
2025-03-01
DOI
https://doi.org/10.1200/po.24.00266
Primary Topic
Melanoma and MAPK Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Multiomics Identifies Potential Molecular Profiles Associated With Outcomes After BRAF-Targeted Therapy in Patients With BRAF V600E-Mutated Advanced Solid Tumors

Martin Højgaard, Christina Westmose Yde, Martina Amnitzbøll Eriksen, Annelaura Bach Nielsen et al.
JCO Precision Oncology
Melanoma and MAPK Pathways
article

Multiomics Identifies Potential Molecular Profiles Associated With Outcomes After BRAF-Targeted Therapy in Patients With BRAF V600E-Mutated Advanced Solid Tumors

Martin Højgaard, Christina Westmose Yde, Martina Amnitzbøll Eriksen, Annelaura Bach Nielsen, Camilla Qvortrup, Filip Mundt, Kristoffer Staal Rohrberg, Iben Spanggaard, Lise Barlebo Ahlborn, Ulrik Lassen, Matthias Mann, Å. Hansen
article en

Abstract

Using a multiomic approach, we identified molecular alterations associated with treatment outcomes. The potential of analyzing multiomic data is promising and should be prioritized in translational cancer research to uncover the full potential within precision oncology.

JCO Precision OncologyVol. 9(9)
University of Copenhagen (DK), Novo Nordisk Foundation (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK)
Good health and well-being
Openalex Percentile: Top 96%
Melanoma and MAPK Pathways
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Multiomics Identifies Potential Molecular Profiles Associated With Outcomes After BRAF-Targeted Therapy in Patients With BRAF V600E-Mutated Advanced Solid Tumors — Martin Højgaard, Christina Westmose Yde, et al. · JCO Precision Oncology (2025) | TGRS Research Map | TGRS