A real-life evaluation of SNOT-22 domains in a cohort of CRSwNP patients treated with biologic therapies for 12 months
Our real-life study describes the kinetics over the first year of treatment with mAbs in CRSwNP, showing different patterns in reducing symptoms and improving Health Related Quality of Life (HRQoL). SNOT-22 with the factorial division in 4 domains can help distinguish fast responders from low or non-responders to a mAb based on clinical response after 1 month and more accurately assign the right mAb to the right patient.
Authors
- Cristiano Caruso (ORCID: https://orcid.org/0000-0001-7631-029X)
- Giuseppe Murdaca (ORCID: https://orcid.org/0000-0002-6403-6905)
- Giulia Anna Maria Luigia Costanzo (ORCID: https://orcid.org/0000-0003-2269-0439)
- Davide Firinu (ORCID: https://orcid.org/0000-0002-5768-391X)
- Maria Pina Barca
- Silvia Canalis
- Giada Sambugaro (ORCID: https://orcid.org/0009-0007-6815-5614)
- Andrea Giovanni Ledda (ORCID: https://orcid.org/0009-0003-5456-2359)
- Paolo Serra
- Stefano Del Giacco (ORCID: https://orcid.org/0000-0002-4517-1749)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Cagliari (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ospedale San Paolo (IT)
- Azienda Ospedaliero-Universitaria Cagliari (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Genoa (IT)
Publication Details
- Journal
- World Allergy Organization Journal
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.waojou.2025.101041
- Citations
- 1
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.85