To evaluate the effect of oral zinc supplementation on salivary MMP-8 levels in periodontitis: A randomized, double-blind, placebo-controlled study
When compared with scaling and root planing alone, the administration of oral zinc supplementation along with scaling and root planing showed greater reduction in clinical parameters and salivary MMP-8 levels in patients with moderate to severe periodontitis. Zinc has a positive effect in management of periodontitis and can serve as an easy, cost effective, harmless and beneficial adjunct in treatment of periodontitis.
Authors
- Pramod K. Rastogi (ORCID: https://orcid.org/0000-0002-5516-135X)
- Pavitra Rastogi (ORCID: https://orcid.org/0000-0001-5894-5371)
- Umesh Pratap Verma (ORCID: https://orcid.org/0000-0002-7008-3185)
- Rameshwari Singhal (ORCID: https://orcid.org/0000-0002-5389-7689)
- Nitu Nigam (ORCID: https://orcid.org/0000-0002-5426-1527)
- Nand Lal (ORCID: https://orcid.org/0000-0002-5227-5255)
- Vishakha Gupta
- Anjani Kumar Pathak (ORCID: https://orcid.org/0000-0003-4076-952X)
- Sadhna Ajay
Institutions
- Babu Banarasi Das University (IN)
- King George's Medical University (IN)
- Autonomous Healthcare (US)
Publication Details
- Journal
- Journal of Oral Biology and Craniofacial Research
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1016/j.jobcr.2025.02.013
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00