Effect of adjuvant cisternostomy on the prognosis of patients with severe traumatic brain injury: A single center’s retrospective study
This study evaluates the efficacy of adjuvant cisternostomy (AC) versus decompressive craniectomy (DC) in managing severe traumatic brain injury (sTBI). A single-center retrospective analysis of consecutive sTBI patients treated with AC or DC alone (2018-2019) revealed that the AC group exhibited significantly lower intracranial pressure and higher Glasgow Coma Scale scores compared with the DC group (P < .05). Cerebrospinal fluid and serum analyses demonstrated reduced interleukin-1β and nerve fiber layer levels in the AC group. In addition, the AC group required lower mannitol dosages and showed fewer postoperative complications. Six-month follow-up indicated a statistically higher rate of good prognosis in the AC group (P < .05). These findings suggest that AC is superior to DC in reducing intracranial pressure, mitigating neurological damage, and improving clinical outcomes in sTBI patients.
Authors
- Bin Wang (ORCID: https://orcid.org/0000-0003-3981-8849)
- Qiquan Zhang (ORCID: https://orcid.org/0009-0004-9944-9103)
- ShiQi Cheng (ORCID: https://orcid.org/0000-0002-4613-2303)
- Raorao Yuan
- Peng Chen (ORCID: https://orcid.org/0000-0002-1536-4945)
- Wei Qiang Wang (ORCID: https://orcid.org/0000-0002-1430-1360)
- Wenxin Zheng (ORCID: https://orcid.org/0000-0002-5199-0847)
- Dongdong Xu (ORCID: https://orcid.org/0000-0002-2265-2574)
- Yi Zhuo
- D. Shu (ORCID: https://orcid.org/0009-0000-3036-4663)
Institutions
- Nanchang University (CN)
- Jiujiang First People's Hospital (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- County Hospital (GB)
Publication Details
- Journal
- Medicine
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1097/md.0000000000041699
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00