ANKRD11 as a potential biomarker for brain metastasis from lung adenocarcinoma via cerebrospinal fluid liquid biopsy
Our study highlights the potential of ctDNA-based CSF liquid biopsy in identifying BM-LUAD, and the efficacy in revealing novel biomarkers for BM-LUAD. Data analyses and functional assays indicated <i>ANKRD11</i> as a predictive biomarker for BM-LUAD. This result addresses, to some extent, the existing gap in biomarkers for BM-LUAD.
Authors
- J. Li (ORCID: https://orcid.org/0009-0009-1397-2734)
- Zhitong Li (ORCID: https://orcid.org/0000-0002-0567-9724)
- Tongyan Liu (ORCID: https://orcid.org/0000-0001-5677-4513)
- Qinhong Sun (ORCID: https://orcid.org/0009-0007-1321-201X)
- Fancheng Meng (ORCID: https://orcid.org/0000-0003-0330-2023)
- Peng Xing (ORCID: https://orcid.org/0000-0002-9017-8771)
- Siwei Wang (ORCID: https://orcid.org/0000-0001-5077-060X)
- Rong Yin (ORCID: https://orcid.org/0000-0002-9744-4251)
- Qinglin Wang (ORCID: https://orcid.org/0000-0002-8286-6566)
- Zhijun Xia
Institutions
- Jiangsu Cancer Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.21037/tlcr-24-800
- Citations
- 1
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52